Singlobet’s patented core technology centres on a novel process that takes a certain class of very important water insoluble organic dyes and renders them temporarily water soluble. This “transient solubility” enables these dyes to be deposited onto (or into) a wide range of target materials (including organic tissue) in a manner that would not be possible any other way. Until now, these dyes would have had to be either chemically (and permanently) modified or dissolved in organic solvents to achieve this result. However, these existing processes have several inherent disadvantages. Firstly, chemical modification changes the properties of the dye, which can be disadvantageous in many situations. Secondly, the use of organic solvents can have a deleterious effect on the target material. Thirdly, organic solvents have potential toxicity and disposal problems so that their use is totally precluded if the dye is to enter living tissue. Singlobet’s elegantly simple and environmentally safe technology eliminates these problems and affords a new and novel way to apply this important class of dyes.